SCHEMBL3157012

SCHEMBL3157012

O=C(O)[C@@H]1CCCCC12C(=O)OC2=O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
HSD11B1 P28845 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL231600 1.00 LMNA (0.36) LMNATSHRHSD11B1
SCHEMBL9016948 0.94 TP53 (0.31) LMNATSHR
SCHEMBL1481003 0.71 TP53 (0.36) LMNATSHR
SCHEMBL8621964 0.71 TP53 (0.32) LMNATSHR
SCHEMBL19433874 0.69 HSD11B1 (0.37) LMNATSHRHSD11B1
SCHEMBL25218266 0.67 GRM4 (0.38) LMNATSHRHSD11B1
SCHEMBL14536263 0.67 HSD11B1 (0.36) LMNATSHRHSD11B1
SCHEMBL643447 0.67 TP53 (0.32) LMNATSHR
SCHEMBL11362509 0.67 GAA (0.33)
SCHEMBL8621959 0.67 MAPK1 (0.33) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703010-B2 Curing agent for epoxy resins and epoxy resin compositions MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-04-22 US disclosed
EP-1754734-B1 CURING AGENT FOR EPOXY RESINS AND EPOXY RESIN COMPOSITIONS MITSUBISHI GAS CHEMICAL CO (JP) 2010-03-10 EP disclosed
US-20080306223-A1 Curing Agent for Epoxy Resins and Epoxy Resin Compositions OKOSHI ATSUSHI 2008-12-11 US disclosed
EP-1754734-A1 CURING AGENT FOR EPOXY RESINS AND EPOXY RESIN COMPOSITIONS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-02-21 EP disclosed