Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753881 | 0.83 | HPGD (0.51) | HPGDALDH1A1NR1H4KMT2ACHRNA1 | |
| SCHEMBL902163 | 0.83 | MAPT (0.50) | HPGDALDH1A1KMT2APOLBNPSR1 | |
| SCHEMBL926068 | 0.81 | HPGD (0.47) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9435241 | 0.81 | HPGD (0.55) | HPGDALDH1A1NR1H4KMT2ACHRNA1 | |
| SCHEMBL436283 | 0.81 | PTPRC (0.52) | HPGDALDH1A1NR1H4KMT2ACHRNA1 | |
| SCHEMBL9435285 | 0.81 | HPGD (0.49) | HPGDALDH1A1NR1H4KMT2ACHRNA1 | |
| SCHEMBL902528 | 0.81 | CHRNA1 (0.42) | HPGDALDH1A1KMT2ACHRNA1CHRNG | |
| SCHEMBL2707408 | 0.80 | NR1H4 (0.43) | HPGDALDH1A1NR1H4KMT2APOLB | |
| SCHEMBL15492067 | 0.80 | HPGD (0.49) | HPGDALDH1A1KMT2APOLBNPC1 | |
| SCHEMBL938064 | 0.80 | HPGD (0.46) | HPGDALDH1A1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653000-B2 | Imine substituted 2,4-diaryl-pyrroline derivatives as pesticides | BASF SE (DE) | 2014-02-18 | — | — | US | disclosed |
| EP-2621900-A1 | IMINE SUBSTITUTED 2, 4 - DIARYL - PYRROLINE DERIVATIVES AS PESTICIDES | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| US-20130190378-A1 | Imine substituted 2,4-diaryl-pyrroline derivatives as pesticides | BASF SE (DE) | 2013-07-25 | — | — | US | disclosed |
| WO-2012042007-A1 | IMINE SUBSTITUTED 2, 4 - DIARYL - PYRROLINE DERIVATIVES AS PESTICIDES | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190378-A1 | Imine substituted 2,4-diaryl-pyrroline derivatives as pesticides | DDT, PIR, INMT | HPGD 1545/4885ALDH1A1 2168/4885NR1H4 4735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.