SCHEMBL9017382

SCHEMBL9017382

CC1COC(=O)c2ccc(cc2)C(=O)O1.O=C(O)c1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RXRA P19793 5/20 0.40
RXRB P28702 5/20 0.40
TDP1 Q9NUW8 1/20 0.40
BCL2L1 Q07817 1/20 0.40
BAD Q92934 1/20 0.40
HRH3 Q9Y5N1 1/20 0.39
GRIK1 P39086 1/20 0.39
GRIK2 Q13002 1/20 0.39
GRIK3 Q13003 1/20 0.39
HSD17B10 Q99714 1/20 0.38
EGFR P00533 1/20 0.38
RXRG P48443 2/20 0.38
BCL2 P10415 1/20 0.38
TNKS O95271 1/20 0.38
POLB P06746 1/20 0.37
SRD5A2 P31213 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL1325176 0.88 TDP1 (0.41) RXRARXRBTDP1EGFRRXRG
SCHEMBL4168935 0.87 GRM2 (0.37)
SCHEMBL66015 0.85 MAOA (0.37) POLB
Succinic Acid SCHEMBL1325312 0.83 HTT (0.40) HRH3
Ethylene SCHEMBL11664467 0.82 MAOA (0.35) POLB
SCHEMBL9017397 0.81 L3MBTL1 (0.40) TDP1POLB
Adipic Acid SCHEMBL1326117 0.81 HTT (0.38) TDP1HRH3
Isophthalic Acid SCHEMBL1325184 0.81 TDP1 (0.36) TDP1HRH3HSD17B10
Sebacic Acid SCHEMBL1325801 0.79 NAAA (0.39) HRH3
SCHEMBL10579283 0.79 PKM (0.42) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0674587-A4 IMPROVED BIAXIALLY ORIENTED COPOLYESTER FILM FOR MAGNETIC RECORDING MEDIA. HOECHST AG (DE) 1996-02-28 EP disclosed
EP-0674586-A4 A BIAXIALLY ORIENTED TWO-LAYER COPOLYESTER FILM FOR CAPACITOR DIELECTRIC USE. HOECHST AG (DE) 1996-02-28 EP disclosed
EP-0675803-A1 BIAXIALLY ORIENTED COPOLYESTER/POLYOLEFIN BI- OR TRILAYER FILM AND METHOD FOR MAKING THE SAME HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-11 EP disclosed
EP-0674587-A1 IMPROVED BIAXIALLY ORIENTED COPOLYESTER FILM FOR MAGNETIC RECORDING MEDIA HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed
EP-0674586-A1 A BIAXIALLY ORIENTED TWO-LAYER COPOLYESTER FILM FOR CAPACITOR DIELECTRIC USE HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed
EP-0671990-A1 BIAXIALLY ORIENTED COPOLYESTER FILM FOR CAPACITOR DIELECTRIC USE OR THERMAL TRANSFER RIBBON USE HOECHST AKTIENGESELLSCHAFT (DE) 1995-09-20 EP disclosed
EP-0675803-A4 BIAXIALLY ORIENTED COPOLYESTER/POLYOLEFIN BI- OR TRILAYER FILM AND METHOD FOR MAKING THE SAME. HOECHST AG (DE) 1995-08-10 EP disclosed
EP-0671990-A4 BIAXIALLY ORIENTED COPOLYESTER FILM FOR CAPACITOR DIELECTRIC USE OR THERMAL TRANSFER RIBBON USE. HOECHST AG (DE) 1995-08-01 EP disclosed
WO-1994013475-A1 BIAXIALLY ORIENTED COPOLYESTER/POLYOLEFIN BI- OR TRILAYER FILM AND METHOD FOR MAKING THE SAME HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-23 WO disclosed
WO-1994013482-A1 A BIAXIALLY ORIENTED TWO-LAYER COPOLYESTER FILM FOR CAPACITOR DIELECTRIC USE HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-23 WO disclosed
WO-1994013483-A1 IMPROVED BIAXIALLY ORIENTED COPOLYESTER FILM FOR MAGNETIC RECORDING MEDIA HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-23 WO disclosed
WO-1994013464-A1 BIAXIALLY ORIENTED COPOLYESTER FILM FOR CAPACITOR DIELECTRIC USE OR THERMAL TRANSFER RIBBON USE HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-23 WO disclosed