Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 14/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.45 |
| ▸ | NQO2 | P16083 | 12/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638887 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2LY96MTNR1AMTNR1BNQO2 | |
| SCHEMBL8643630 | 0.83 | MTNR1A (0.60) | SMN1; SMN2MTNR1AMTNR1BNQO2 | |
| SCHEMBL8641851 | 0.81 | MTNR1A (0.45) | LY96MTNR1AMTNR1BNQO2ALDH1A1 | |
| SCHEMBL8639949 | 0.81 | MTNR1A (0.49) | SMN1; SMN2MTNR1AMTNR1BNQO2ALDH1A1 | |
| SCHEMBL8646700 | 0.81 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8646238 | 0.80 | MTNR1A (0.48) | MTNR1AMTNR1BNQO2LMNAKMT2A | |
| SCHEMBL9017429 | 0.80 | MTNR1A (0.49) | SMN1; SMN2MTNR1AMTNR1BNQO2ALDH1A1 | |
| SCHEMBL8641737 | 0.80 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2ALDH1A1MAPT | |
| SCHEMBL8640441 | 0.79 | NQO2 (0.63) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8638751 | 0.79 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747345-A2 | Ethylamido fluorenes and improved method of making same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | claimed |
| EP-0747345-A2 | Ethylamido fluorenes and improved method of making same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |