Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192019 | 0.84 | GAA (0.50) | ELANEMMP1MMP3MMP9TP53 | |
| SCHEMBL7194468 | 0.84 | GAA (0.41) | ELANEMMP1MMP3MMP9TP53 | |
| SCHEMBL1358142 | 0.83 | L3MBTL1 (0.41) | ELANEMMP1MMP3MMP9TP53 | |
| SCHEMBL9017602 | 0.81 | GBA1 (0.49) | MMP1MMP3MMP9TP53GAA | |
| SCHEMBL9017626 | 0.81 | GBA1 (0.49) | MMP1MMP3MMP9TP53GAA | |
| SCHEMBL7203140 | 0.78 | CYP3A4 (0.34) | ELANEMMP1MMP3MMP9TP53 | |
| SCHEMBL818514 | 0.76 | — | — | |
| SCHEMBL24162980 | 0.74 | MMP1 (0.32) | MMP1MMP9 | |
| SCHEMBL6850956 | 0.68 | ELANE (0.59) | ELANEMMP1MMP3MMP9TP53 | |
| SCHEMBL35761 | 0.68 | ALDH1A1 (0.36) | ELANEMMP1MMP3MMP9TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004599-B1 | Process for the preparation of an n-alkyl lactam with improved colour quality | BASF SE (DE) | 2011-11-09 | — | — | EP | claimed |
| US-6639093-B2 | Reacting benzyl chloride with hydroxybenzoic acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-28 | — | — | US | claimed |
| US-20030053964-A1 | Process for the preparation of hydroxybenzoic benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | US | claimed |
| EP-1249443-A2 | Process for the production of hydroxybenzoic acid benzyl esters | BAYER AG (DE) | 2002-10-16 | — | — | EP | claimed |
| EP-2486090-B1 | PLASTICIZED POLYMERIC COMPOSITIONS | ISP INVESTMENTS INC (US) | 2017-12-06 | — | — | EP | disclosed |
| US-9359486-B2 | Plasticized polymeric compositions | ISP INVESTMENTS INC. (US) | 2016-06-07 | — | — | US | disclosed |
| CN-102770404-B | The manufacture method of the ester cpds containing α, β-unsaturated link(age) | JX NIPPON OIL & ENERGY CORP. (JP) | 2016-01-27 | — | — | CN | disclosed |
| US-8946468-B2 | Process for producing ester compound having an internal unsaturated bond or cyclic olefin | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2015-02-03 | — | — | US | disclosed |
| CN-102224125-B | Process for producing ketone | NIPPON OIL CORP | 2013-11-20 | — | — | CN | disclosed |
| US-8507728-B2 | Method for manufacturing ketone | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20120316360-A1 | PROCESS FOR PRODUCING ESTER COMPOUND HAVING a,ß-UNSATURATED BOND | OSAKA UNIVERSITY (JP) | 2012-12-13 | — | — | US | disclosed |
| CN-102770404-A | Process for producing ester compound having alpha, beta-unsaturated bond | JX NIPPON OIL & ENERGY CORP | 2012-11-07 | — | — | CN | disclosed |
| CN-102548942-A | Method for producing ketone | JX NIPPON OIL & ENERGY CORP | 2012-07-04 | — | — | CN | disclosed |
| US-20110288340-A1 | METHOD FOR MANUFACTURING KETONE | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2011-11-24 | — | — | US | disclosed |
| CN-102224125-A | Process for producing ketone | NIPPON OIL CORP | 2011-10-19 | — | — | CN | disclosed |
| EP-2364965-A1 | KETONE MANUFACTURING METHOD | JX Nippon Oil & Energy Corporation (JP) | 2011-09-14 | — | — | EP | disclosed |
| WO-2011044018-A1 | PLASTICIZED POLYMERIC COMPOSITIONS | ISP INVESTMENTS INC. (US) | 2011-04-14 | — | — | WO | disclosed |
| US-6639093-B2 | Reacting benzyl chloride with hydroxybenzoic acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-28 | — | — | US | disclosed |
| US-20030053964-A1 | Process for the preparation of hydroxybenzoic benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | US | disclosed |
| EP-1249443-A2 | Process for the production of hydroxybenzoic acid benzyl esters | BAYER AG (DE) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288340-A1 | METHOD FOR MANUFACTURING KETONE | CBR1, CBR3, ODC1 | ELANE 4315/4885MMP1 2780/4885MMP3 3686/4885 |
| US-20120316360-A1 | PROCESS FOR PRODUCING ESTER COMPOUND HAVING a,ß-UNSATURATED BOND | COASY, OXER1, ACSL1 | ELANE 2555/4885MMP1 3533/4885MMP3 4362/4885 |
| US-20030053964-A1 | Process for the preparation of hydroxybenzoic benzyl esters | HAAO, HPD, HACL2 | ELANE 2990/4885MMP1 3317/4885MMP3 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.