SCHEMBL1358142

SCHEMBL1358142

CCCCC1C(=O)N1CO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
ELANE P08246 2/20 0.40
MMP1 P03956 1/20 0.36
MMP3 P08254 1/20 0.36
MMP9 P14780 1/20 0.36
TP53 P04637 2/20 0.35
GAA P10253 1/20 0.35
ALDH1A1 P00352 4/20 0.35
CYP3A4 P08684 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP2C19 P33261 1/20 0.35
PTGS1 P23219 1/20 0.35
RAB9A P51151 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
GBA1 P04062 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7192019 0.81 GAA (0.50) L3MBTL1ELANEMMP1MMP3MMP9
SCHEMBL7194468 0.81 GAA (0.41) ELANEMMP1MMP3MMP9TP53
SCHEMBL9017626 0.78 GBA1 (0.49) MMP1MMP3MMP9TP53GAA
SCHEMBL9017602 0.78 GBA1 (0.49) MMP1MMP3MMP9TP53GAA
SCHEMBL7203140 0.75 CYP3A4 (0.34) L3MBTL1ELANEMMP1MMP3MMP9
SCHEMBL818514 0.73
SCHEMBL6850956 0.69 ELANE (0.59) ELANEMMP1MMP3MMP9TP53
SCHEMBL11535750 0.68 GBA1 (0.40) TP53GAAALDH1A1LMNAPTGS1
Methyl Alcohol SCHEMBL5460389 0.67 ELANE (0.37) ELANEMMP1MMP3MMP9TP53
SCHEMBL7887401 0.65 PTGS1 (0.42) TP53GAAALDH1A1CYP1A2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110277844-A1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF HERCULES LLC 2011-11-17 US claimed
US-12552931-B2 Dihydroxy lactam based polymers, compositions and applications thereof ISP INVESTMENTS LLC (US) 2026-02-17 US disclosed
US-20220315761-A1 DIHYDROXY LACTAM BASED POLYMERS, COMPOSITIONS AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2022-10-06 US disclosed
CN-113631632-A Dihydroxylactam-based polymers, compositions thereof and uses thereof ISP投资有限公司 2021-11-09 CN disclosed
CN-109153933-B Carbon dioxide co-fluid 艾默生环境优化技术有限公司 2021-09-03 CN disclosed
US-9993559-B2 N-alkyl lactam ethers, and compositions and uses thereof ISP INVESTMENTS LLC (US) 2018-06-12 US disclosed
EP-2346909-B1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF ISP INVESTMENTS INC (US) 2018-05-16 EP disclosed
US-9885002-B2 Carbon dioxide co-fluid EMERSON CLIMATE TECHNOLOGIES, INC. (US) 2018-02-06 US disclosed
US-20170313954-A1 CARBON DIOXIDE CO-FLUID EMERSON CLIMATE TECHNOLOGIES, INC. (US) 2017-11-02 US disclosed
WO-2017189897-A1 CARBON DIOXIDE CO-FLUID EMERSON CLIMATE TECHNOLOGIES, INC. (US) 2017-11-02 WO disclosed
US-20140045698-A1 N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF ISP INVESTMENTS INC. (US) 2014-02-13 US disclosed
EP-2501728-A1 ALKYL LACTAM ESTER POLYMERS, AND USES THEREOF Isp Investments Inc. (US) 2012-09-26 EP disclosed
US-20120149861-A1 LACTAM-BASED COMPOUNDS WITH A URETHANE OR UREA FUNCTIONAL GROUP, AND USES THEREOF ISP INVESTMENTS LLC 2012-06-14 US disclosed
US-20120148514-A1 N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF ISP INVESTMENTS INC. (US) 2012-06-14 US disclosed
WO-2012068001-A1 N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF ISP INVESTMENTS INC. (US) 2012-05-24 WO disclosed
US-20110277844-A1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF HERCULES LLC 2011-11-17 US disclosed
EP-2346909-A1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF Isp Investments Inc. (US) 2011-07-27 EP disclosed
WO-2011063208-A1 ALKYL LACTAM ESTER POLYMERS, AND USES THEREOF ISP INVESTMENTS INC. (US) 2011-05-26 WO disclosed
WO-2011022457-A1 LACTAM-BASED COMPOUNDS WITH A URETHANE OR UREA FUNCTIONAL GROUP, AND USES THEREOF ISP INVESTMENTS INC. (US) 2011-02-24 WO disclosed
WO-2010056934-A1 POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF ISP INVESTMENTS INC. (US) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552931-B2 Dihydroxy lactam based polymers, compositions and applications thereof PARG, GNE, PGLS L3MBTL1 2436/4885ELANE 188/4885MMP1 1485/4885
US-20170313954-A1 CARBON DIOXIDE CO-FLUID CA9, TDO2, CPS1 L3MBTL1 3375/4885ELANE 2079/4885MMP1 2549/4885
US-20140045698-A1 N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF USP8, MLST8, CYP2C8 L3MBTL1 4202/4885ELANE 470/4885MMP1 3411/4885
US-20120149861-A1 LACTAM-BASED COMPOUNDS WITH A URETHANE OR UREA FUNCTIONAL GROUP, AND USES THEREOF CUTA, PUF60, PAM L3MBTL1 2498/4885ELANE 926/4885MMP1 612/4885
US-20120148514-A1 N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF USP8, MLST8, CYP2C8 L3MBTL1 4202/4885ELANE 470/4885MMP1 3411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.