SCHEMBL9017635

SCHEMBL9017635

c1ccc(N=Nc2ccccc2-c2cccc3cc4ccc5cc6cc7ccccc7cc6cc5c4cc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP7 Q9BQF6 3/20 0.42
CASP3 P42574 2/20 0.42
SENP6 Q9GZR1 2/20 0.42
SENP8 Q96LD8 1/20 0.42
MEN1 O00255 7/20 0.36
KMT2A Q03164 7/20 0.36
NPC1 O15118 5/20 0.36
RAB9A P51151 4/20 0.36
THRB P10828 1/20 0.36
ALDH1A1 P00352 5/20 0.35
HSD17B10 Q99714 4/20 0.35
HIF1A Q16665 4/20 0.35
CYP1B1 Q16678 1/20 0.35
CYP1A2 P05177 4/20 0.35
HPGD P15428 2/20 0.35
HSP90AA1 P07900 1/20 0.35
MAPK1 P28482 5/20 0.34
TDP1 Q9NUW8 4/20 0.34
L3MBTL1 Q9Y468 4/20 0.34
MAPT P10636 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28961947 0.94 SENP7 (0.47) SENP7CASP3SENP6SENP8MEN1
SCHEMBL29978043 0.94 SENP7 (0.47) SENP7CASP3SENP6SENP8MEN1
SCHEMBL3089392 0.81 ALDH1A1 (0.46) SENP7CASP3SENP6SENP8MEN1
SCHEMBL1974253 0.80 ALDH1A1 (0.52) MEN1KMT2ATHRBALDH1A1HSD17B10
SCHEMBL2213062 0.80 ALDH1A1 (0.52) MEN1KMT2ATHRBALDH1A1HSD17B10
SCHEMBL29203671 0.80 SENP7 (0.44) SENP7CASP3SENP6SENP8MEN1
SCHEMBL4650692 0.79 CASP3 (0.52) SENP7CASP3SENP6SENP8MEN1
SCHEMBL29203673 0.78 CASP3 (0.42) SENP7CASP3SENP6SENP8MEN1
SCHEMBL28366772 0.76 CASP3 (0.49) SENP7CASP3SENP6SENP8MEN1
SCHEMBL11779555 0.76 ALDH1A1 (0.58) ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0494756-B1 Aromatic polyamide oligomers SHOWA HIGHPOLYMER (JP) 1996-04-03 EP disclosed
US-5247047-A Curable polymers to form heat resistant moldings SHOWA HIGHPOLYMER CO., LTD. (JP) 1993-09-21 US disclosed
EP-0494756-A2 Aromatic polyamide oligomers SHOWA HIGHPOLYMER CO., LTD. (JP) 1992-07-15 EP disclosed
US-4927900-A Aromatic polyamidoimides having maleimido end groups RHONE-POULENC CHIMIE (FR) 1990-05-22 US disclosed