Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 3/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017854 | 1.00 | CACNA1B (0.34) | CACNA1BADH1CADH1AAOC3CHRNB2 | |
| Maleic Acid SCHEMBL9681627 | 0.89 | MEN1 (0.32) | JAK3PRMT3ALDH1A1MEN1KMT2A | |
| SCHEMBL9017856 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9017850 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9017918 | 0.78 | BCHE (0.34) | JAK3PRMT3ALDH1A1POLBTSHR | |
| Maleic Acid SCHEMBL9017934 | 0.74 | BCHE (0.31) | JAK3PRMT3ALDH1A1MEN1KMT2A | |
| Fumaric Acid SCHEMBL9017938 | 0.74 | BCHE (0.31) | JAK3PRMT3ALDH1A1MEN1KMT2A | |
| SCHEMBL9017936 | 0.73 | MEN1 (0.30) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| Dimethylcarbate SCHEMBL9679433 | 0.71 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| Dimethylcarbate SCHEMBL9679440 | 0.71 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0477903-A2 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-01 | — | — | EP | disclosed |