Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 5/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL9017934 | 0.95 | BCHE (0.31) | BCHENCEH1ACHEPRMT3ALDH1A1 | |
| Fumaric Acid SCHEMBL9017938 | 0.95 | BCHE (0.31) | BCHENCEH1ACHEPRMT3ALDH1A1 | |
| SCHEMBL9017936 | 0.89 | MEN1 (0.30) | ALDH1A1MAPK1 | |
| SCHEMBL9017843 | 0.82 | RAB9A (0.38) | BCHENCEH1ALDH1A1TSHRGAA | |
| SCHEMBL9017846 | 0.82 | RAB9A (0.38) | BCHENCEH1ALDH1A1TSHRGAA | |
| SCHEMBL9017879 | 0.79 | ACHE (0.39) | BCHENCEH1ACHETSHR | |
| SCHEMBL9017892 | 0.79 | ACHE (0.39) | BCHENCEH1ACHETSHR | |
| SCHEMBL9017889 | 0.79 | ACHE (0.39) | BCHENCEH1ACHETSHR | |
| SCHEMBL9017875 | 0.79 | ACHE (0.39) | BCHENCEH1ACHETSHR | |
| SCHEMBL9017858 | 0.78 | CACNA1B (0.34) | PRMT3ALDH1A1POLBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0477903-A2 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-01 | — | — | EP | disclosed |