Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017918 | 0.89 | BCHE (0.34) | ALDH1A1MAPK1 | |
| Maleic Acid SCHEMBL9017934 | 0.86 | BCHE (0.31) | MEN1ALDH1A1MAPK1KMT2ASMN1; SMN2 | |
| Fumaric Acid SCHEMBL9017938 | 0.86 | BCHE (0.31) | MEN1ALDH1A1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9017932 | 0.76 | MAPT (0.31) | — | |
| SCHEMBL9017854 | 0.73 | CACNA1B (0.34) | MEN1ALDH1A1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9017858 | 0.73 | CACNA1B (0.34) | MEN1ALDH1A1MAPK1KMT2ASMN1; SMN2 | |
| Maleic Acid SCHEMBL9681627 | 0.73 | MEN1 (0.32) | MEN1ALDH1A1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9017843 | 0.72 | RAB9A (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9017846 | 0.72 | RAB9A (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9017875 | 0.69 | ACHE (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0477903-A2 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-01 | — | — | EP | disclosed |