Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017917 | 0.89 | MAPT (0.37) | MAPT | |
| SCHEMBL9017921 | 0.89 | MAPT (0.37) | MAPT | |
| Maleic Acid SCHEMBL9017929 | 0.87 | MAPT (0.34) | MAPT | |
| SCHEMBL9017939 | 0.81 | NCEH1 (0.34) | — | |
| SCHEMBL9017940 | 0.81 | NCEH1 (0.34) | — | |
| SCHEMBL9017936 | 0.76 | MEN1 (0.30) | — | |
| SCHEMBL9017888 | 0.76 | BCHE (0.35) | — | |
| Dimethylcarbate SCHEMBL9681182 | 0.74 | MAPT (0.36) | MAPT | |
| Dimethylcarbate SCHEMBL9681187 | 0.74 | MAPT (0.36) | MAPT | |
| Maleic Acid SCHEMBL9679921 | 0.73 | ATG4B (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0477903-A2 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-01 | — | — | EP | disclosed |