Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018277 | 0.89 | POLB (0.42) | ALDH1A1MAPTPOLBTDP1MEN1 | |
| SCHEMBL9018020 | 0.89 | HPGD (0.43) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL9018550 | 0.88 | SMN1; SMN2 (0.44) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL9136958 | 0.88 | POLB (0.41) | ALDH1A1MAPTPOLBTDP1MEN1 | |
| SCHEMBL9018317 | 0.87 | HPGD (0.43) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL9018491 | 0.87 | MAPT (0.40) | ALDH1A1MAPTPOLBTDP1MEN1 | |
| SCHEMBL7862781 | 0.86 | POLB (0.43) | ALDH1A1MAPTPOLBTDP1MEN1 | |
| SCHEMBL9018002 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AHPGDLMNA | |
| SCHEMBL9018239 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7867840 | 0.84 | POLB (0.42) | ALDH1A1MAPTPOLBTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |