Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018239 | 0.96 | ALDH1A1 (0.40) | HPGDSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL9018002 | 0.95 | ALDH1A1 (0.40) | HPGDSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL9018430 | 0.92 | ACACB (0.40) | HPGDSMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL9018131 | 0.92 | HPGD (0.41) | HPGDSMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL9018120 | 0.91 | CA2 (0.45) | HPGDSMN1; SMN2LMNAL3MBTL1KDM4E | |
| SCHEMBL9018187 | 0.90 | CA2 (0.45) | HPGDSMN1; SMN2LMNAL3MBTL1KDM4E | |
| SCHEMBL9018502 | 0.90 | GABRA5 (0.43) | SMN1; SMN2ALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL9018483 | 0.89 | GABRA5 (0.43) | SMN1; SMN2ALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL9018236 | 0.89 | HPGD (0.50) | HPGDSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL9017981 | 0.89 | ALDH1A1 (0.41) | HPGDSMN1; SMN2ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |