Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018213 | 0.95 | SMN1; SMN2 (0.45) | KMT2AMAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL9018272 | 0.95 | RAB9A (0.41) | KMT2AGABRA5MAPTALDH1A1RAB9A | |
| SCHEMBL9018238 | 0.93 | KMT2A (0.43) | KMT2AMAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL9018269 | 0.92 | GABRA5 (0.44) | KMT2AGABRA5MAPTALDH1A1RAB9A | |
| SCHEMBL9018147 | 0.91 | RAB9A (0.44) | KMT2AMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9018099 | 0.90 | SMN1; SMN2 (0.43) | KMT2AGABRA5MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9018341 | 0.90 | RAB9A (0.50) | KMT2AMAPTRAB9ASMN1; SMN2BCL2L1 | |
| SCHEMBL9017996 | 0.90 | RAB9A (0.40) | KMT2AMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9018134 | 0.89 | RAB9A (0.49) | KMT2AMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9018092 | 0.89 | SMN1; SMN2 (0.47) | KMT2AMAPTALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |