Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018272 | 0.92 | RAB9A (0.41) | RAB9AKAT6ASMN1; SMN2KMT2AHPGD | |
| SCHEMBL9018136 | 0.92 | RAB9A (0.53) | RAB9AKAT6ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9018134 | 0.91 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL9017996 | 0.90 | RAB9A (0.40) | RAB9AKAT6ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL9017995 | 0.90 | KMT2A (0.43) | RAB9ASMN1; SMN2KMT2AHPGDMAPT | |
| SCHEMBL9018213 | 0.90 | SMN1; SMN2 (0.45) | RAB9AKAT6ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL9018147 | 0.89 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL9018099 | 0.89 | SMN1; SMN2 (0.43) | RAB9AKAT6ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL9018154 | 0.89 | RAB9A (0.49) | RAB9AKAT6ANPC1SMN1; SMN2HPGD | |
| SCHEMBL9018360 | 0.89 | RAB9A (0.50) | RAB9AKAT6ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |