Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018429 | 0.92 | NPC1 (0.51) | LMNAP4HTMCA2CA9OPRM1 | |
| SCHEMBL9018444 | 0.91 | SCN3A (0.50) | SCN3AEPHX2ALDH1A1LMNAP4HTM | |
| SCHEMBL9018204 | 0.90 | NPC1 (0.46) | EPHX2ALDH1A1P4HTMOPRM1OPRD1 | |
| SCHEMBL9018013 | 0.89 | P4HTM (0.58) | P4HTM | |
| SCHEMBL9018251 | 0.89 | MAPT (0.49) | LMNAP4HTMOPRM1OPRD1OPRK1 | |
| SCHEMBL9018017 | 0.88 | EGFR (0.45) | EPHX2P4HTMCA12CA9OPRM1 | |
| SCHEMBL9018143 | 0.88 | SCN3A (0.48) | SCN3AEPHX2ALDH1A1LMNAP4HTM | |
| SCHEMBL9018412 | 0.87 | OPRM1 (0.48) | SCN3AP4HTMOPRM1OPRD1OPRK1 | |
| SCHEMBL9018309 | 0.87 | SCN3A (0.46) | SCN3AEPHX2ALDH1A1LMNAP4HTM | |
| SCHEMBL9018048 | 0.86 | NPC1 (0.52) | P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |