Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018051 | 0.90 | ALDH1A1 (0.45) | P4HTMALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL9018110 | 0.89 | ALDH1A1 (0.46) | P4HTMALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL9140246 | 0.88 | P4HTM (0.50) | BCL2L1MCL1P4HTMALDH1A1POLB | |
| SCHEMBL9018569 | 0.87 | ALDH1A1 (0.43) | P4HTMALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL9018506 | 0.87 | PPARA (0.56) | BCL2L1MCL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9018079 | 0.87 | ALDH1A1 (0.42) | P4HTMALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL9018108 | 0.87 | ALDH1A1 (0.44) | P4HTMALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL9018313 | 0.87 | ALDH1A1 (0.44) | P4HTMALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL7870461 | 0.85 | ALDH1A1 (0.49) | P4HTMALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL7869439 | 0.85 | RAB9A (0.42) | BCL2L1MCL1P4HTMALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |