Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SGMS1 | Q86VZ5 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018495 | 0.92 | POLB (0.43) | PTPN1ALDH1A1LMNAPOLBSGMS1 | |
| SCHEMBL9018028 | 0.92 | PTPN1 (0.53) | PTPN1ALDH1A1LMNAPOLBSGMS1 | |
| SCHEMBL9018343 | 0.91 | CA1 (0.43) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL9018068 | 0.91 | P4HTM (0.43) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL7862669 | 0.91 | CYP1A2 (0.45) | PTPN1ALDH1A1LMNAPOLBSGMS1 | |
| SCHEMBL9018274 | 0.89 | RAB9A (0.48) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL7871649 | 0.89 | ALDH1A1 (0.44) | PTPN1ALDH1A1LMNAPOLBSGMS1 | |
| SCHEMBL9018311 | 0.88 | P4HTM (0.42) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL9018356 | 0.87 | ALDH1A1 (0.41) | ALDH1A1OPRM1OPRD1OPRK1P4HTM | |
| SCHEMBL9139519 | 0.87 | P4HTM (0.48) | PTPN1ALDH1A1LMNAPOLBSGMS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |