Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018360 | 0.92 | RAB9A (0.50) | RAB9ACHRM2NPC1SMN1; SMN2HPGD | |
| SCHEMBL9018116 | 0.92 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2HPGDPOLB | |
| SCHEMBL9018331 | 0.92 | RAB9A (0.40) | RAB9ASMN1; SMN2HPGDCASP3 | |
| SCHEMBL9018136 | 0.92 | RAB9A (0.53) | RAB9ACHRM2NPC1SMN1; SMN2HPGD | |
| SCHEMBL9018066 | 0.90 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL9018286 | 0.90 | GABRA5 (0.40) | RAB9ASMN1; SMN2HPGDCASP3 | |
| SCHEMBL9018177 | 0.89 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2HPGDCASP3 | |
| SCHEMBL9018378 | 0.89 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2HPGDPOLB | |
| SCHEMBL9018341 | 0.89 | RAB9A (0.50) | RAB9ACHRM2NPC1SMN1; SMN2HPGD | |
| SCHEMBL9018075 | 0.89 | SMN1; SMN2 (0.43) | RAB9ASMN1; SMN2KAT6ABCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |