Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.57 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018333 | 0.89 | P4HTM (0.64) | P4HTMTSHRHCRTR1MCL1PIN1 | |
| SCHEMBL9018353 | 0.87 | P4HTM (0.60) | P4HTMHTR6TSHRHCRTR1MCL1 | |
| SCHEMBL9018214 | 0.84 | P4HTM (0.55) | P4HTMMCL1 | |
| SCHEMBL9574712 | 0.79 | P4HTM (0.57) | P4HTMTSHRHCRTR1MCL1PIN1 | |
| SCHEMBL9574792 | 0.79 | P4HTM (0.54) | P4HTMKCNA5TSHRSLC6A9HCRTR1 | |
| SCHEMBL9574775 | 0.79 | P4HTM (0.59) | P4HTMHTR6TSHRHCRTR1MCL1 | |
| SCHEMBL9018122 | 0.78 | HTT (0.50) | P4HTMEPHX2POLB | |
| SCHEMBL9018055 | 0.78 | SMN1; SMN2 (0.42) | P4HTMMCL1 | |
| SCHEMBL9018203 | 0.78 | EGFR (0.42) | P4HTMEPHX2 | |
| SCHEMBL9018456 | 0.78 | P4HTM (0.57) | P4HTMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |