Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574712 | 0.90 | P4HTM (0.57) | P4HTMTSHRGABRA5SLC16A3PIN1 | |
| SCHEMBL7869169 | 0.85 | GABRA5 (0.44) | P4HTMGABRA5 | |
| SCHEMBL9574792 | 0.84 | P4HTM (0.54) | P4HTMTSHRSLC16A3PIN1EPHX2 | |
| SCHEMBL7869455 | 0.83 | P4HTM (0.57) | P4HTMGABRA5MCL1EGFR | |
| SCHEMBL9018333 | 0.83 | P4HTM (0.64) | P4HTMTSHRSLC16A3PIN1EPHX2 | |
| SCHEMBL9574778 | 0.82 | P4HTM (0.43) | P4HTMMCL1CYP3A4CYP2C19EGFR | |
| SCHEMBL9018353 | 0.81 | P4HTM (0.60) | P4HTMTSHRGABRA5SLC16A3PIN1 | |
| SCHEMBL9018246 | 0.79 | P4HTM (0.57) | P4HTMTSHRSLC16A3PIN1EPHX2 | |
| SCHEMBL7871628 | 0.78 | HTT (0.53) | P4HTMEPHX2ALDH1A1HSD17B10 | |
| SCHEMBL9517968 | 0.78 | P4HTM (0.69) | P4HTMTSHRSLC16A3MCL1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |