Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574775 | 0.90 | P4HTM (0.59) | P4HTMGABRA5EPHX2ALDH1A1MCL1 | |
| SCHEMBL9574747 | 0.87 | POLB (0.56) | P4HTMALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL9574792 | 0.86 | P4HTM (0.54) | P4HTMEPHX2MCL1SLC16A3PIN1 | |
| SCHEMBL8869036 | 0.85 | P4HTM (0.69) | P4HTMALDH1A1HPGDMCL1KDM4E | |
| SCHEMBL9018333 | 0.85 | P4HTM (0.64) | P4HTMEPHX2MCL1SLC16A3POLB | |
| SCHEMBL7871609 | 0.84 | P4HTM (0.55) | P4HTMGABRA5HPGDMCL1 | |
| SCHEMBL9018353 | 0.82 | P4HTM (0.60) | P4HTMGABRA5EPHX2ALDH1A1HPGD | |
| SCHEMBL7867912 | 0.80 | EGFR (0.47) | P4HTMGABRA5EPHX2ALDH1A1HPGD | |
| SCHEMBL7869173 | 0.80 | RAB9A (0.44) | P4HTMGABRA5ALDH1A1HPGD | |
| SCHEMBL7871663 | 0.80 | EPHX2 (0.49) | P4HTMGABRA5EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |