Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574712 | 0.86 | P4HTM (0.57) | P4HTMTSHREDNRAEPHX2MCL1 | |
| SCHEMBL8871170 | 0.86 | P4HTM (0.65) | P4HTMTSHREDNRASLC6A9MCL1 | |
| SCHEMBL9018333 | 0.85 | P4HTM (0.64) | P4HTMTSHREDNRAEPHX2MCL1 | |
| SCHEMBL9574775 | 0.84 | P4HTM (0.59) | P4HTMTSHREPHX2MCL1HCRTR1 | |
| SCHEMBL9018353 | 0.79 | P4HTM (0.60) | P4HTMTSHREDNRAEPHX2MCL1 | |
| SCHEMBL9018246 | 0.79 | P4HTM (0.57) | P4HTMTSHREDNRASLC6A9EPHX2 | |
| SCHEMBL9516257 | 0.75 | P4HTM (0.64) | P4HTMTSHREDNRAMCL1HCRTR1 | |
| SCHEMBL9018361 | 0.74 | P4HTM (0.77) | P4HTMTSHREDNRAHCRTR1 | |
| SCHEMBL9141420 | 0.74 | P4HTM (0.72) | P4HTMTSHREDNRAMCL1HCRTR1 | |
| SCHEMBL9574747 | 0.74 | POLB (0.56) | P4HTMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |