Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018198 | 0.94 | OPRM1 (0.40) | OPRM1OPRD1OPRK1CA1CA2 | |
| SCHEMBL9018129 | 0.93 | CA1 (0.46) | OPRM1OPRD1OPRK1CA1CA2 | |
| SCHEMBL9018406 | 0.92 | RAB9A (0.45) | OPRM1OPRD1OPRK1CA1CA2 | |
| SCHEMBL9018343 | 0.92 | CA1 (0.43) | OPRM1OPRD1OPRK1CA1CA2 | |
| SCHEMBL9018495 | 0.92 | POLB (0.43) | OPRM1OPRD1OPRK1CA1CA2 | |
| SCHEMBL9018435 | 0.91 | ALDH1A1 (0.39) | OPRM1OPRD1OPRK1CA1CA2 | |
| SCHEMBL9018301 | 0.91 | CA1 (0.41) | OPRM1OPRD1OPRK1CA1CA2 | |
| SCHEMBL9018066 | 0.90 | RAB9A (0.48) | OPRM1OPRD1OPRK1CA1CA2 | |
| SCHEMBL9018505 | 0.88 | MAPT (0.50) | OPRM1OPRD1OPRK1CA1CA2 | |
| SCHEMBL9018288 | 0.88 | CA1 (0.43) | OPRM1OPRD1OPRK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |