Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018159 | 0.92 | KMT2A (0.49) | RAB9ACTSLCTSSROCK2MAPT | |
| SCHEMBL9018210 | 0.90 | SMN1; SMN2 (0.45) | RAB9AMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9018062 | 0.89 | SMN1; SMN2 (0.45) | RAB9AMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9138678 | 0.89 | CA1 (0.54) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9018249 | 0.86 | CA1 (0.57) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9018393 | 0.86 | CXCR1 (0.47) | CA1CA2CA9RAB9AROCK2 | |
| SCHEMBL9018080 | 0.86 | TGM2 (0.46) | ROCK2ROCK1MAPTALDH1A1LMNA | |
| SCHEMBL9018146 | 0.86 | CA1 (0.56) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9018058 | 0.85 | ACACB (0.43) | RAB9AROCK2ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL9018073 | 0.85 | EGFR (0.46) | CA1CA2CA9RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |