Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | GRN | P28799 | 2/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018289 | 0.91 | P4HTM (0.46) | GABRA5P4HTMMCL1MAPTCTSA | |
| SCHEMBL9018431 | 0.90 | CXCR2 (0.47) | GABRA5CXCR1CXCR2POLBRAB9A | |
| SCHEMBL9018485 | 0.88 | GABRA5 (0.49) | GABRA5P4HTMMAPTCXCR1CXCR2 | |
| SCHEMBL9017990 | 0.87 | GABRA5 (0.43) | GABRA5P4HTMMCL1MAPTCTSA | |
| SCHEMBL9018052 | 0.86 | P4HTM (0.60) | GABRA5P4HTMMAPTCXCR2OPRM1 | |
| SCHEMBL9018160 | 0.86 | GABRA5 (0.51) | GABRA5P4HTMMAPTCXCR2OPRM1 | |
| SCHEMBL9018394 | 0.85 | GABRA5 (0.51) | GABRA5P4HTMMAPTCXCR2OPRM1 | |
| SCHEMBL9143098 | 0.83 | P4HTM (0.53) | GABRA5P4HTMMCL1MAPTTDP1 | |
| SCHEMBL9018048 | 0.82 | NPC1 (0.52) | P4HTMMCL1MAPTPOLBRAB9A | |
| SCHEMBL7862809 | 0.82 | GABRA5 (0.43) | GABRA5P4HTMMAPTOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |