Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.52 |
| ▸ | CYCS | P99999 | 4/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572426 | 0.82 | TOP1 (0.53) | TOP1CYCSABCG2MEN1KMT2A | |
| SCHEMBL10897459 | 0.80 | TOP1 (0.53) | TOP1CYCSABCG2ENPP2FFAR1 | |
| SCHEMBL5013766 | 0.79 | TERT (0.50) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL16912677 | 0.76 | TOP1 (0.54) | TOP1CYCSABCG2ENPP2STAT3 | |
| SCHEMBL16923748 | 0.76 | ALDH1A1 (0.55) | TOP1CYCSABCG2ENPP2MEN1 | |
| Acetic Acid SCHEMBL9639956 | 0.75 | TOP1 (0.67) | TOP1CYCSABCG2ENPP2STAT3 | |
| SCHEMBL30180821 | 0.75 | TOP1 (0.57) | TOP1CYCSENPP2STAT3STAT1 | |
| SCHEMBL30136 | 0.75 | TOP1 (0.64) | TOP1CYCSENPP2STAT3STAT1 | |
| SCHEMBL29405434 | 0.75 | TOP1 (0.64) | TOP1CYCSENPP2STAT3STAT1 | |
| SCHEMBL9018604 | 0.74 | TOP1 (0.52) | TOP1CYCSABCG2ENPP2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748226-A1 | BLOCK COPOLYMERS | NYCOMED IMAGING AS (NO) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995022991-A2 | BLOCK COPOLYMERS | NYCOMED IMAGING AS (NO) | 1995-08-31 | — | — | WO | disclosed |