Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610125 | 0.88 | SLC9A1 (0.61) | SLC9A1 | |
| SCHEMBL9018688 | 0.81 | SLC9A1 (0.67) | SLC9A1 | |
| SCHEMBL9018700 | 0.79 | SLC9A1 (0.39) | SLC9A1 | |
| SCHEMBL7797862 | 0.79 | EGLN1 (0.43) | SLC9A1 | |
| SCHEMBL9018697 | 0.78 | PKM (0.50) | KDM4ENPSR1 | |
| SCHEMBL5190885 | 0.77 | SLC9A1 (0.59) | SLC9A1KDM4E | |
| SCHEMBL8059436 | 0.75 | NR1H4 (0.46) | — | |
| SCHEMBL8440231 | 0.75 | CYP1A2 (0.43) | — | |
| SCHEMBL7764035 | 0.74 | SLC9A1 (0.45) | SLC9A1 | |
| SCHEMBL8442624 | 0.74 | MCL1 (0.45) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |