Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608691 | 0.92 | SLC9A1 (0.40) | SLC9A1LMNAALDH1A1 | |
| SCHEMBL9018712 | 0.85 | SLC9A1 (0.47) | SLC9A1LMNA | |
| SCHEMBL9018721 | 0.83 | PLAU (0.41) | SLC9A1PLAU | |
| SCHEMBL9018711 | 0.83 | PLAU (0.41) | SLC9A1PLAU | |
| SCHEMBL16528351 | 0.82 | MEN1 (0.41) | LMNA | |
| SCHEMBL9018731 | 0.81 | SLC9A1 (0.42) | SLC9A1PLAULMNAALDH1A1 | |
| SCHEMBL9018682 | 0.80 | SLC9A1 (0.46) | SLC9A1 | |
| SCHEMBL8610762 | 0.79 | SLC9A1 (0.47) | SLC9A1LMNA | |
| SCHEMBL24616176 | 0.79 | POLB (0.41) | LMNAALDH1A1 | |
| SCHEMBL9018718 | 0.78 | SLC9A1 (0.41) | SLC9A1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |