Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612355 | 0.93 | TDP1 (0.47) | SLC9A1MEN1KMT2ATDP1TTR | |
| SCHEMBL3158027 | 0.81 | MEN1 (0.57) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL9018719 | 0.80 | AKR1B1 (0.46) | SLC9A1MEN1KMT2ATDP1TTR | |
| SCHEMBL9018732 | 0.80 | FFAR4 (0.40) | SLC9A1KMT2APIM1 | |
| SCHEMBL9018694 | 0.79 | SLC9A1 (0.44) | SLC9A1 | |
| SCHEMBL16961592 | 0.78 | MEN1 (0.43) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL9018736 | 0.78 | SLC9A1 (0.40) | SLC9A1ALDH1A1LMNA | |
| SCHEMBL9018712 | 0.78 | SLC9A1 (0.47) | SLC9A1MEN1KMT2ATDP1TTR | |
| SCHEMBL8612597 | 0.77 | CFTR (0.48) | SLC9A1MEN1KMT2ATDP1TTR | |
| SCHEMBL9018666 | 0.77 | PIM1 (0.40) | SLC9A1KMT2APIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |