Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485183 | 0.89 | NR1H2 (0.41) | NR1H2HSD17B10ALOX15CYP3A4HIF1A | |
| SCHEMBL8779795 | 0.86 | CYP2C9 (0.37) | HSD17B10CYP2C9CYP2C19MMP2MMP8 | |
| SCHEMBL8779780 | 0.78 | NR1H2 (0.41) | NR1H2HSD17B10CYP3A4MEN1LMNA | |
| SCHEMBL3896041 | 0.76 | HSD17B10 (0.52) | HSD17B10CYP3A4HIF1AALDH1A1MEN1 | |
| SCHEMBL25314314 | 0.74 | MAPT (0.51) | NR1H2HSD17B10ALOX15CYP3A4HIF1A | |
| SCHEMBL8779807 | 0.74 | CYP2A6 (0.42) | HSD17B10ALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL3901375 | 0.74 | HPGD (0.43) | ALDH1A1CA2MEN1LMNAMAPT | |
| SCHEMBL3724500 | 0.74 | NR1H2 (0.50) | NR1H2HSD17B10ALOX15CYP3A4HIF1A | |
| SCHEMBL8488661 | 0.74 | IDO1 (0.39) | HSD17B10CYP2C9CYP2C19MMP2MMP8 | |
| SCHEMBL10338884 | 0.74 | NR1H2 (0.50) | NR1H2HSD17B10ALOX15CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742201-A1 | PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |