Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488666 | 0.89 | HPGD (0.38) | HPGDTDP1ACHEDNMT1KMT2A | |
| SCHEMBL8779795 | 0.86 | CYP2C9 (0.37) | — | |
| SCHEMBL8779780 | 0.78 | NR1H2 (0.41) | HPGDKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL1454134 | 0.76 | TDP1 (0.44) | HPGDTDP1ACHEDNMT1KMT2A | |
| SCHEMBL3896041 | 0.76 | HSD17B10 (0.52) | HPGDTDP1KMT2AMAPTLMNA | |
| SCHEMBL29021173 | 0.74 | TDP1 (0.42) | HPGDTDP1ACHEDNMT1KMT2A | |
| SCHEMBL8779807 | 0.74 | CYP2A6 (0.42) | KMT2AALDH1A1MEN1TRPA1MAPK1 | |
| SCHEMBL2321466 | 0.74 | LMNA (0.47) | HPGDTDP1ACHEDNMT1KMT2A | |
| SCHEMBL9018796 | 0.74 | NR1H2 (0.50) | HPGDTDP1ACHEKMT2AMAPT | |
| SCHEMBL8488661 | 0.74 | IDO1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1431302-B1 | PROCESS FOR SYNTHESIS OF ORGANOMETALLIC COMPOUNDS | SEKISUI CHEMICAL CO LTD (JP) | 2009-03-18 | — | — | EP | disclosed |
| US-7098355-B2 | Process for synthesis of organometallic compounds | SEKISUI CHEMICAL CO., LTD. (JP) | 2006-08-29 | — | — | US | disclosed |
| CN-1747913-A | Zero-valence transition metal complex and method of synthesizing organometallic compound from the same as starting material | SEKISUI CHEMICAL CO LTD (JP) | 2006-03-15 | — | — | CN | disclosed |
| US-20060030723-A1 | Process for synthesis of organometallic compounds | SEKISUI CHEMICAL CO., LTD. (JP) | 2006-02-09 | — | — | US | disclosed |
| EP-1431302-A1 | PROCESS FOR SYNTHESIS OF ORGANOMETALLIC COMPOUNDS | SEKISUI CHEMICAL CO., LTD. (JP) | 2004-06-23 | — | — | EP | disclosed |
| EP-0742201-A1 | PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030723-A1 | Process for synthesis of organometallic compounds | CYP4F12, CYP4F2, CYP4F11 | HPGD 2774/4885TDP1 4062/4885ACHE 4521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.