Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804935 | 0.87 | TSHR (0.47) | TSHRSAE1UBA2MAPTALDH1A1 | |
| SCHEMBL1247034 | 0.80 | TSHR (0.61) | TSHRMAPTALDH1A1NPSR1CYP1A2 | |
| SCHEMBL13714153 | 0.79 | VNN1 (0.54) | TSHRHTTLMNAMEN1KMT2A | |
| SCHEMBL9018905 | 0.77 | TSHR (0.54) | TSHRMAPTALDH1A1NPSR1CYP1A2 | |
| SCHEMBL10727676 | 0.77 | TSHR (0.54) | TSHRMAPTALDH1A1NPSR1CYP1A2 | |
| SCHEMBL11464001 | 0.77 | TSHR (0.54) | TSHRMAPTALDH1A1NPSR1CYP1A2 | |
| SCHEMBL3880496 | 0.77 | TSHR (0.54) | TSHRMAPTALDH1A1NPSR1CYP1A2 | |
| SCHEMBL2585010 | 0.77 | KEAP1 (0.63) | TSHRSAE1UBA2MAPTCYP3A4 | |
| SCHEMBL8691983 | 0.77 | TSHR (0.48) | TSHRSAE1UBA2ALDH1A1LOXL2 | |
| SCHEMBL6164527 | 0.75 | PARP1 (0.47) | SAE1UBA2MAPTALDH1A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543573-A | INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0462456-B1 | Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0462456-A1 | Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |