Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776607 | 0.84 | KEAP1 (0.86) | KEAP1HSPA5CA12CA2CA9 | |
| SCHEMBL30616875 | 0.84 | KEAP1 (0.86) | KEAP1HSPA5CA12CA2CA9 | |
| SCHEMBL8702909 | 0.84 | TAAR1 (0.46) | KEAP1HSPA5LOXL2CYP2A6CA12 | |
| SCHEMBL7031631 | 0.81 | KEAP1 (0.63) | KEAP1HSPA5CA12CA2BCL2 | |
| SCHEMBL4003141 | 0.81 | KEAP1 (0.63) | KEAP1HSPA5CA12CA2BCL2 | |
| Water SCHEMBL27955473 | 0.80 | KEAP1 (0.72) | KEAP1HSPA5BCL2BCL2L1ALOX5 | |
| SCHEMBL68653 | 0.78 | KEAP1 (1.00) | KEAP1HSPA5BCL2BCL2L1ALOX5 | |
| SCHEMBL8925742 | 0.78 | KEAP1 (0.76) | KEAP1HSPA5CA12CA2CA9 | |
| SCHEMBL29506902 | 0.78 | KEAP1 (1.00) | KEAP1HSPA5BCL2BCL2L1ALOX5 | |
| SCHEMBL6532341 | 0.78 | LOXL2 (0.48) | CYP11B1CYP11B2LOXL2SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120192231-A | Copper-based complex Cu (dppf) (BH)4) Application in nucleophilic addition reaction of arylboronic acid | 安徽大学 | 2025-06-24 | — | — | CN | disclosed |
| US-11667606-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667606-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| CN-113784950-A | Novel thyromimetic agents | 速通医疗公司 | 2021-12-10 | — | — | CN | disclosed |
| US-20210053917-A1 | NOVEL THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2021-02-25 | — | — | US | disclosed |
| US-20210053917-A1 | NOVEL THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2021-02-25 | — | — | US | disclosed |
| US-8048897-B2 | Cyclohexane derivative, prodrug thereof and salt thereof, and therapeutic agent containing the same for diabetes | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-11-01 | — | — | US | disclosed |
| US-20080318874-A1 | Novel Cyclohexane Derivative, Prodrug Thereof and Salt Thereof, and Therapeutic Agent Containing the Same for Diabetes | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-12-25 | — | — | US | disclosed |
| EP-1783110-A1 | NOVEL CYCLOHEXANE DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667606-B2 | Thyromimetics | TPO, TSHR, TTR | KEAP1 2106/4885HSPA5 3213/4885CYP11B1 301/4885 |
| US-20080318874-A1 | Novel Cyclohexane Derivative, Prodrug Thereof and Salt Thereof, and Therapeutic Agent Containing the Same for Diabetes | SLC5A1, GPR119, SLC5A2 | KEAP1 901/4885HSPA5 2445/4885CYP11B1 12/4885 |
| US-20210053917-A1 | NOVEL THYROMIMETICS | TPO, TSHR, CHRM1 | KEAP1 1628/4885HSPA5 2993/4885CYP11B1 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.