Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.52 |
| ▸ | MTOR | P42345 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.46 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.46 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419902 | 0.89 | CNR1 (0.57) | EPHX2MTORMEN1MAPTHTT | |
| SCHEMBL13964164 | 0.83 | MTOR (0.50) | EPHX2MTORMEN1MAPTHTT | |
| SCHEMBL9018847 | 0.82 | SAE1 (0.49) | EPHX2MEN1MAPTHTTRAB9A | |
| SCHEMBL9018855 | 0.81 | RAB9A (0.54) | MEN1RAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL13964323 | 0.80 | TRPV1 (0.51) | EPHX2MEN1MAPTRAB9AKMT2A | |
| SCHEMBL5809373 | 0.79 | EPHX2 (0.85) | EPHX2MTORMEN1MAPTHTT | |
| SCHEMBL9508161 | 0.78 | KDM4E (0.52) | EPHX2MTORMEN1MAPTHTT | |
| SCHEMBL9419947 | 0.76 | PAX8 (0.49) | MEN1MAPTKMT2APRKAB2PRKAG1 | |
| SCHEMBL6339735 | 0.74 | PTPN1 (0.56) | RAB9ANPC1 | |
| SCHEMBL13521652 | 0.74 | PTGS1 (0.56) | MTORMEN1MAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543573-A | INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0462456-B1 | Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0462456-A1 | Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |