Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419902 | 0.84 | CNR1 (0.57) | GRIK1EPHX2RAB9ACNR1MTOR | |
| SCHEMBL9018884 | 0.81 | TP53 (0.58) | KDM4ERAB9ANPC1CNR1MEN1 | |
| SCHEMBL9018847 | 0.79 | SAE1 (0.49) | EPHX2RAB9ANPC1FPR2MEN1 | |
| SCHEMBL9018902 | 0.78 | EPHX2 (0.52) | EPHX2RAB9ANPC1MTORBAZ1A | |
| SCHEMBL9018831 | 0.77 | TP53 (0.70) | EPHX2RAB9ANPC1MEN1MAPT | |
| SCHEMBL14186097 | 0.77 | TP53 (0.70) | EPHX2RAB9ANPC1MEN1MAPT | |
| SCHEMBL12386612 | 0.77 | TP53 (0.70) | EPHX2RAB9ANPC1MEN1MAPT | |
| SCHEMBL9018855 | 0.76 | RAB9A (0.54) | GRIK1RAB9ANPC1CNR1MEN1 | |
| SCHEMBL13521652 | 0.76 | PTGS1 (0.56) | RAB9AMTORBAZ1AMEN1MAPT | |
| SCHEMBL161516 | 0.75 | BAZ1A (0.71) | GRIK1EPHX2RAB9ANPC1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553284-A1 | SEMICARBAZONE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |
| WO-1992006076-A1 | SEMICARBAZONE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-16 | — | — | WO | disclosed |