SCHEMBL9019044

SCHEMBL9019044

N#Cc1c(Br)c(Br)n(O)c1-c1ccc(Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.38
MAOB P27338 3/20 0.38
GRIA2 P42262 1/20 0.36
GRIA4 P48058 1/20 0.36
USP2 O75604 1/20 0.36
THRB P10828 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPSR1 Q6W5P4 6/20 0.35
KDM4E B2RXH2 9/20 0.34
HPGD P15428 5/20 0.34
LMNA P02545 4/20 0.34
POLB P06746 1/20 0.34
ALDH1A1 P00352 5/20 0.33
MAPT P10636 4/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
RXFP1 Q9HBX9 2/20 0.33
HTT P42858 2/20 0.33
HSD17B10 Q99714 2/20 0.33
PPARG P37231 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9019133 0.83 MAPK14 (0.41) MAOAMAOBHPGDLMNAPOLB
SCHEMBL9019046 0.80 L3MBTL1 (0.41) MAOAMAOBGRIA2GRIA4USP2
SCHEMBL9019106 0.77 MAOB (0.41) MAOAMAOBGRIA2GRIA4USP2
SCHEMBL9519227 0.74 GRIA2 (0.42) MAOAGRIA2GRIA4USP2THRB
SCHEMBL9019103 0.74 MEN1 (0.33) GRIA2GRIA4USP2THRBL3MBTL1
SCHEMBL9702818 0.72 GRIA4 (0.37) GRIA2GRIA4USP2THRBL3MBTL1
SCHEMBL9019009 0.72 MAOB (0.45) MAOAMAOBGRIA2GRIA4USP2
SCHEMBL9218224 0.69 MEN1 (0.37) GRIA2GRIA4L3MBTL1KDM4EHPGD
SCHEMBL9213698 0.69 ABCB1 (0.41) GRIA2GRIA4USP2THRBL3MBTL1
SCHEMBL7548622 0.69 KDM4E (0.39) MAOAGRIA2GRIA4USP2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434940-B1 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID CO (US) 1996-05-29 EP claimed
US-5102904-A N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS AMERICAN CYANAMID COMPANY (US) 1992-04-07 US claimed
EP-0434940-A2 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1991-07-03 EP claimed
JP-3251561-A None JP disclosed
EP-0434940-B1 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID CO (US) 1996-05-29 EP disclosed
US-5399716-A N-oxygenated arylpyrrole insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1995-03-21 US disclosed
US-5347016-A N-oxygenated arylpyrrole intermediates for insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1994-09-13 US disclosed
US-5232979-A Insecticides, miticides, nematocides AMERICAN CYANAMID COMPANY (US) 1993-08-03 US disclosed
US-5102904-A N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS AMERICAN CYANAMID COMPANY (US) 1992-04-07 US disclosed
JP-H03251561-A N-OXYGENATED ARYLPYRROLE, METHOD FOR CONTROLLING INSECT, NEMATODE AND ACARID BY USING THE SAME, AND PRODUCTION OF THE COMPOUND AMERICAN CYANAMID CO 1991-11-11 JP disclosed