Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11627313 | 0.83 | ALDH1A1 (0.46) | CTSAALDH1A1HTTL3MBTL1GAA | |
| SCHEMBL7901954 | 0.76 | CTSA (0.48) | CTSAALDH1A1PDPK1SLC6A3GRM5 | |
| SCHEMBL11172666 | 0.73 | KMT2A (0.47) | CTSAPDPK1RAB9ASLC6A3TSHR | |
| SCHEMBL8432353 | 0.73 | CTSA (0.46) | CTSAPDPK1NPC1RAB9ASLC6A3 | |
| SCHEMBL6848050 | 0.73 | ALOX5 (0.52) | CTSAPDPK1NPC1RAB9ASLC6A3 | |
| SCHEMBL2593428 | 0.73 | CTSA (0.46) | CTSAPDPK1NPC1RAB9ASLC6A3 | |
| SCHEMBL16055379 | 0.72 | ALDH1A1 (0.43) | CTSAALDH1A1HTTPDPK1GAA | |
| SCHEMBL181005 | 0.72 | TSHR (0.56) | ALDH1A1HTTL3MBTL1GAANPC1 | |
| SCHEMBL11631498 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HTTL3MBTL1GAANPC1 | |
| SCHEMBL6218499 | 0.71 | LMNA (0.37) | CTSAALDH1A1PDPK1GRM5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3843724-A1 | BENZIMIDAZOLE COMPOUNDS AND USE THEREOF FOR TREATING ALZHEIMER'S DISEASE OR HUNTINGTON'S DISEASE | National Health Research Institutes (TW) | 2021-07-07 | — | — | EP | disclosed |
| WO-2020047360-A1 | BENZIMIDAZOLE COMPOUNDS AND USE THEREOF FOR TREATING ALZHEIMER'S DISEASE OR HUNTINGTON'S DISEASE | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2020-03-05 | — | — | WO | disclosed |
| WO-2014057139-A2 | PRECURSOR MOLECULE FOR THE SYNTHESIS OF D-LUCIFERIN | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2014-04-17 | — | — | WO | disclosed |
| EP-2719703-A1 | Precursor molecule for the synthesis of D-luciferin | Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) | 2014-04-16 | — | — | EP | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |
| US-4081544-A | ANTIDEPRESSANTS | SCHERING CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-3932431-A | ANTIDEPRESSANT, ANTIINFLAMMATORY | SCHERING CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |