Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RPA1 | P27694 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | ALAD | P13716 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019189 | 0.78 | MEN1 (0.44) | NPC1RAB9ASMN1; SMN2RPA1MAOA | |
| SCHEMBL2215605 | 0.72 | NOTUM (0.53) | NPC1RAB9ASMN1; SMN2RPA1TP53 | |
| SCHEMBL16403258 | 0.70 | NOTUM (0.70) | NPC1RAB9AALDH1A1NOTUM | |
| SCHEMBL2215793 | 0.69 | CNR2 (0.54) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL9019021 | 0.68 | ALOX15 (0.48) | SMN1; SMN2RPA1L3MBTL1TSHRPPP1CA | |
| SCHEMBL6498907 | 0.67 | ALDH1A1 (0.61) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL10995741 | 0.67 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2RPA1L3MBTL1 | |
| SCHEMBL3417670 | 0.66 | TSHR (0.70) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL809394 | 0.66 | ALDH1A1 (0.59) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL28746452 | 0.66 | CYP1A2 (0.58) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434940-B1 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID CO (US) | 1996-05-29 | — | — | EP | disclosed |
| US-5399716-A | N-oxygenated arylpyrrole insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-5347016-A | N-oxygenated arylpyrrole intermediates for insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| US-5232979-A | Insecticides, miticides, nematocides | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5102904-A | N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0434940-A2 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |