SCHEMBL9019256

SCHEMBL9019256

CCCCCc1cc(C(=O)O)cn1O

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.45
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
RARA P10276 1/20 0.44
MAPT P10636 1/20 0.44
MTOR P42345 1/20 0.44
KMT2A Q03164 1/20 0.44
PLA2G2A P14555 1/20 0.41
KDM5A P29375 1/20 0.41
KDM5B Q9UGL1 1/20 0.41
OXER1 Q8TDS5 3/20 0.40
HCAR3 P49019 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
GPR84 Q9NQS5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9150335 0.80 RARB (0.44) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL9019171 0.80 RARB (0.42) RARBMEN1ALDH1A1RARAMAPT
Hexane SCHEMBL29263834 0.71 PLA2G2A (0.62) RARBMEN1ALDH1A1RARAMAPT
Hexane SCHEMBL28903581 0.69 PLA2G2A (0.60) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL27782228 0.69 GPR84 (0.61) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL8413501 0.69 RARB (0.61) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL14118049 0.68 RARB (0.62) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL3293447 0.68 RARB (0.62) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL17060014 0.68 RARB (0.62) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL27760653 0.68 RARB (0.62) RARBMEN1ALDH1A1RARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434940-B1 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID CO (US) 1996-05-29 EP claimed
US-5399716-A N-oxygenated arylpyrrole insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1995-03-21 US claimed
EP-0434940-A2 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1991-07-03 EP claimed
EP-0434940-B1 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID CO (US) 1996-05-29 EP disclosed
US-5399716-A N-oxygenated arylpyrrole insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1995-03-21 US disclosed
US-5347016-A N-oxygenated arylpyrrole intermediates for insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1994-09-13 US disclosed
US-5232979-A Insecticides, miticides, nematocides AMERICAN CYANAMID COMPANY (US) 1993-08-03 US disclosed
US-5102904-A N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS AMERICAN CYANAMID COMPANY (US) 1992-04-07 US disclosed
EP-0434940-A2 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1991-07-03 EP disclosed