Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6071069 | 0.85 | TLR8 (0.50) | MEN1KMT2AGPR84CNR2 | |
| SCHEMBL22748650 | 0.80 | PLA2G2A (0.43) | RARBMEN1KMT2APLA2G2ACNR2 | |
| SCHEMBL9019256 | 0.80 | RARB (0.45) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL7211324 | 0.78 | ALDH1A1 (0.51) | ALDH1A1GPR84OXER1CNR2CDC25A | |
| SCHEMBL9019171 | 0.76 | RARB (0.42) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL6900293 | 0.76 | L3MBTL1 (0.38) | RARBMEN1KMT2APLA2G2A | |
| SCHEMBL7219828 | 0.74 | TP53 (0.46) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL2141794 | 0.74 | GPR84 (0.39) | ALDH1A1KMT2AGPR84CNR2 | |
| SCHEMBL10468639 | 0.72 | CNR2 (0.46) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL4558802 | 0.70 | TLR8 (0.38) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35096-E | Antilipemic, anticholesterol, arteriosclerosis | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-11-21 | — | — | US | disclosed |
| US-5082856-A | Hyperlipemia, arteriosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0347902-A2 | Pyrrolecarboxylic acid derivatives | Mitsubishi Chemical Corporation (JP) | 1989-12-27 | — | — | EP | disclosed |