Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019256 | 0.80 | RARB (0.45) | RARBPLA2G2AMEN1ALDH1A1RARA | |
| SCHEMBL9150335 | 0.76 | RARB (0.44) | RARBPLA2G2AMEN1ALDH1A1RARA | |
| Hexane SCHEMBL29263834 | 0.68 | PLA2G2A (0.62) | RARBPLA2G2AMEN1ALDH1A1RARA | |
| Hexane SCHEMBL28903581 | 0.66 | PLA2G2A (0.60) | RARBPLA2G2AMEN1ALDH1A1RARA | |
| SCHEMBL27782228 | 0.66 | GPR84 (0.61) | RARBPLA2G2AMEN1ALDH1A1RARA | |
| SCHEMBL8413501 | 0.66 | RARB (0.61) | RARBPLA2G2AMEN1ALDH1A1RARA | |
| SCHEMBL6900293 | 0.66 | L3MBTL1 (0.38) | RARBPLA2G2AMEN1KMT2AKDM5A | |
| SCHEMBL29017224 | 0.66 | PPARA (0.55) | RARBPLA2G2APPARGPPARAPLA2G4B | |
| SCHEMBL17060014 | 0.65 | RARB (0.62) | RARBPLA2G2AMEN1ALDH1A1RARA | |
| SCHEMBL14118049 | 0.65 | RARB (0.62) | RARBPLA2G2AMEN1ALDH1A1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434940-B1 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID CO (US) | 1996-05-29 | — | — | EP | disclosed |
| US-5399716-A | N-oxygenated arylpyrrole insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-5347016-A | N-oxygenated arylpyrrole intermediates for insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| US-5232979-A | Insecticides, miticides, nematocides | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5102904-A | N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0434940-A2 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |