SCHEMBL42343

SCHEMBL42343

CN(C)c1ccc(/N=N/c2ccc(S(=O)(=O)Cl)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.69
RAB9A P51151 5/20 0.69
KMT2A Q03164 5/20 0.69
CA12 O43570 4/20 0.69
CA2 P00918 4/20 0.69
CA9 Q16790 4/20 0.69
MEN1 O00255 4/20 0.69
POLB P06746 2/20 0.69
F2 P00734 3/20 0.59
PRSS1 P07477 3/20 0.59
PRSS2 P07478 3/20 0.59
PRSS3 P35030 3/20 0.59
ALDH1A1 P00352 4/20 0.59
TSHR P16473 3/20 0.59
ALOX15 P16050 2/20 0.59
MAPK1 P28482 3/20 0.55
HSD17B10 Q99714 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
KDM4E B2RXH2 2/20 0.51
MAPT P10636 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL42344 1.00 NPC1 (0.69) NPC1RAB9AKMT2ACA12CA2
SCHEMBL295564 0.88 ALDH1A1 (0.61) NPC1RAB9AKMT2ACA12CA2
SCHEMBL29592346 0.86 NPC1 (0.65) NPC1RAB9AKMT2ACA12CA2
SCHEMBL15631068 0.85 NPC1 (0.73) NPC1RAB9AKMT2ACA12CA2
SCHEMBL9620534 0.84 HSD17B10 (0.52) NPC1RAB9AKMT2ACA12CA2
SCHEMBL9019288 0.83 NPC1 (0.71) NPC1RAB9AKMT2ACA12CA2
SCHEMBL13602555 0.83 NPC1 (0.71) NPC1RAB9AKMT2ACA12CA2
SCHEMBL13384871 0.83 NPC1 (0.71) NPC1RAB9AKMT2ACA12CA2
SCHEMBL14419936 0.83 NPC1 (0.71) NPC1RAB9AKMT2ACA12CA2
Methyl Orange SCHEMBL18892 0.81 KMT2A (0.69) NPC1RAB9AKMT2ACA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 799 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118090992-A Method for detecting content of gamma-aminobutyric acid in wine 宜宾五粮液股份有限公司 2024-05-28 CN claimed
WO-2024020584-A2 GRAYSCALE FABRICATION OF 4D MATERIALS UNIVERSITY OF WASHINGTON (US) 2024-01-25 WO claimed
US-20180267067-A1 METHODS FOR BIOANALYSIS OF 6-DIAZO-5-OXO-L-NORLEUCINE (DON) AND OTHER GLUTAMINE ANTAGONISTS THE JOHNS HOPKINS UNIVERSITY (US) 2018-09-20 US claimed
EP-3245296-A1 IN VITRO METHOD FOR ESTIMATING IN VIVO PROTEIN DIGESTIBILITY General Mills, Inc. (US) 2017-11-22 EP claimed
US-9738920-B2 In vitro method for estimating in vivo protein digestibility GENERAL MILLS, INC. (US) 2017-08-22 US claimed
US-9715998-B2 Method for monitoring level of paraben in cosmetics Kaohsuing Medical University (TW) 2017-07-25 US claimed
WO-2016115249-A1 IN VITRO METHOD FOR ESTIMATING IN VIVO PROTEIN DIGESTIBILITY GENERAL MILLS, INC. (US) 2016-07-21 WO claimed
US-20160208309-A1 IN VITRO METHOD FOR ESTIMATING IN VIVO PROTEIN DIGESTIBILITY GENERAL MILLS, INC. 2016-07-21 US claimed
WO-2016112386-A1 METHODS FOR BIOANALYSIS OF 6-DIAZO-5-OXO-L-NORLEUCINE (DON) AND OTHER GLUTAMINE ANTAGONISTS THE JOHNS HOPKINS UNIVERSITY (US) 2016-07-14 WO claimed
US-20160020077-A1 METHOD FOR MONITORING LEVEL OF PARABEN IN COSMETICS KAOHSIUNG MEDICAL UNIVERSITY (CN) 2016-01-21 US claimed
EP-1181556-A1 METHOD TO MEASURE ACYL-COENZYME A ESTERS THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 2002-02-27 EP claimed
US-6251680-B1 REACTING POLYMER WITH AMINE ROHM AND HAAS COMPANY 2001-06-26 US claimed
WO-2001009610-A1 METHOD TO MEASURE ACYL-COENZYME A ESTERS THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 2001-02-08 WO claimed
EP-0606925-B1 A method for derivatizing a 1-amino-1-deoxyoligosaccharide GENZYME CORP (US) 1998-10-07 EP claimed
EP-0785422-A1 Detectable polymers and methods for detecting polymers in aqueous systems ROHM AND HAAS COMPANY (US) 1997-07-23 EP claimed
EP-0389437-B1 Luciferin derivatives NIPPON ZOKI PHARMACEUTICAL CO (JP) 1995-05-24 EP claimed
US-5283353-A Enzymeric cleavage from glycoprotein GENZYME CORPORATION (US) 1994-02-01 US claimed
EP-0389437-A1 Luciferin derivatives NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) 1990-09-26 EP claimed
WO-1989008835-A1 THIOACYLATION PEPTIDE SEQUENCING WITH ACYLATION OF THIAZOLINES BIO-AFFINITY SYSTEMS, INC. (US) 1989-09-21 WO claimed
US-4861726-A Method of thioacylation peptide sequencing with acylation of thiazoloinones BIO-AFFINITY SYSTEMS, INC. (US) 1989-08-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180267067-A1 METHODS FOR BIOANALYSIS OF 6-DIAZO-5-OXO-L-NORLEUCINE (DON) AND OTHER GLUTAMINE ANTAGONISTS GLUL, GLS, ASNS NPC1 2495/4885RAB9A 2269/4885KMT2A 3039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.