Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methyl Orange. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 5/20 | 0.69 |
| ▸ | CA2 known ✓ | P00918 | 5/20 | 0.69 |
| ▸ | PTGS2 known ✓ | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.46 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | CA9 | Q16790 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | F2 | P00734 | 3/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Orange SCHEMBL18893 | 1.00 | KMT2A (0.69) | KMT2ANPC1MEN1CA12CA2 | |
| SCHEMBL27467005 | 0.88 | ALDH1A1 (0.55) | KMT2ANPC1MEN1CA12CA2 | |
| SCHEMBL16163360 | 0.86 | CA12 (0.72) | KMT2ANPC1MEN1CA12CA2 | |
| SCHEMBL15631068 | 0.85 | NPC1 (0.73) | KMT2ANPC1MEN1CA12CA2 | |
| SCHEMBL13602555 | 0.83 | NPC1 (0.71) | KMT2ANPC1MEN1CA12CA2 | |
| SCHEMBL13384871 | 0.83 | NPC1 (0.71) | KMT2ANPC1MEN1CA12CA2 | |
| SCHEMBL14419936 | 0.83 | NPC1 (0.71) | KMT2ANPC1MEN1CA12CA2 | |
| SCHEMBL9019288 | 0.83 | NPC1 (0.71) | KMT2ANPC1MEN1CA12CA2 | |
| SCHEMBL20450 | 0.81 | ALDH1A1 (1.00) | KMT2ANPC1MEN1CA12CA2 | |
| SCHEMBL42343 | 0.81 | NPC1 (0.69) | KMT2ANPC1MEN1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 29675 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260145971-A1 | METHOD OF WATER PURIFICATION | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2026-05-28 | — | — | US | claimed |
| EP-4749288-A1 | COMPOSITIONS FOR DETECTING, CHARACTERIZING, AND REMOVING A BIOFILM | COSA Group GmbH (DE) | 2026-05-27 | — | — | EP | claimed |
| CN-122076471-A | Metal basic salt mineralized membrane, preparation method thereof and application of metal basic salt mineralized membrane serving as heterogeneous catalyst in treatment of organic wastewater | — | 2026-05-26 | — | — | CN | claimed |
| CN-117654641-B | Cellulose-based composite bead for activating peroxymonosulfate degradation dye and preparation method thereof | GUILIN UNIVERSITY OF TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122081455-A | Kit for detecting parotitis pathogen of soft-shelled turtles and application method of kit | — | 2026-05-26 | — | — | CN | claimed |
| CN-121226755-B | Waste PET-based MOFs functional material and preparation method and application thereof | BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122076465-A | Supported ternary heterojunction photocatalytic material and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122081253-A | Laccase mutant and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122072238-A | Membrane material, formic acid sensor and formic acid detection method | 中国科学院大连化学物理研究所 | 2026-05-22 | — | — | CN | claimed |
| CN-118320792-B | Multifunctional bovine hemoglobin composite material, preparation method and application thereof in aspect of dye sewage treatment | 吉林大学 | 2026-05-19 | — | — | CN | claimed |
| US-4060493-A | PIGMENT OR DYE DISPERSED IN GRAFT COPOLYMER AND POLYETHYLENE, POLYETHYLENE WAX OR PARAFFIN WAX | RICOH CO., LTD. (JA) | 1977-11-29 | — | — | US | claimed |
| US-4057029-A | Time-temperature indicator | INFRATAB CORPORATION (US) | 1977-11-08 | — | — | US | claimed |
| US-4042336-A | Time temperature integrating indicator | BIO-MEDICAL SCIENCES INC. (US) | 1977-08-16 | — | — | US | claimed |
| US-4025164-A | Liquid crystal display device for colored display of information with a selective polarizer | BBC BROWN BOVERI & COMPANY LIMITED (CH) | 1977-05-24 | — | — | US | claimed |
| US-4020682-A | Method of measuring mechanical damage to grain | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1977-05-03 | — | — | US | claimed |
| US-3995015-A | Process for making sodium metabisulfite | ALLIED CHEMICAL CORPORATION (US) | 1976-11-30 | — | — | US | claimed |
| US-3994751-A | METHYL ORANGE, ALCOHOLS, XYLENE, ACETIC ACID, THINNERS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1976-11-30 | — | — | US | claimed |
| US-3992149-A | Colorimetric method for the analysis of residual anionic or cationic surfactants | CALSPAN CORPORATION (US) | 1976-11-16 | — | — | US | claimed |
| US-3984204-A | Gas monitors | BRITISH STEEL CORPORATION (EN) | 1976-10-05 | — | — | US | claimed |
| US-3969076-A | Method for the analysis of ionic surfactants | CALSPAN CORPORATION (US) | 1976-07-13 | — | — | US | claimed |