Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5159831 | 0.80 | ALDH1A1 (0.47) | LMNAALDH1A1MAPTCYP3A4NPC1 | |
| SCHEMBL23091851 | 0.75 | TDP1 (0.50) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL408412 | 0.75 | TDP1 (0.50) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL7342834 | 0.74 | LMNA (0.52) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL395491 | 0.74 | MDM2 (0.48) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL8610227 | 0.73 | SMN1; SMN2 (0.41) | LMNAALDH1A1MAPK1MDM2SMN1; SMN2 | |
| SCHEMBL9019293 | 0.73 | MDM2 (0.41) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL9751959 | 0.73 | POLB (0.49) | L3MBTL1LMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30803096 | 0.73 | CES1 (0.56) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL28060783 | 0.73 | TDP1 (0.52) | TDP1L3MBTL1LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748343-B2 | Herbicide/safener combintions | BAYER CROPSCIENCE AG (DE) | 2014-06-10 | — | — | US | disclosed |
| US-20120322657-A1 | HERBICIDE/SAFENER COMBINTIONS | ZIEMER FRANK (DE) | 2012-12-20 | — | — | US | disclosed |
| US-20110053778-A1 | 2-(3-AMINOBENZOYL)-3-CYCLOPROPYL-3-OXOPROPANENITRILES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-03-03 | — | — | US | disclosed |
| WO-2011012248-A2 | 2-(3-AMINOBENZOYL)-3-CYCLOPROPYL-3-OXOPROPANE NITRILES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-02-03 | — | — | WO | disclosed |
| US-20100305200-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. | 2010-12-02 | — | — | US | disclosed |
| EP-1296558-B1 | HERBICIDAL AGENTS | BAYER CROPSCIENCE GMBH (DE) | 2006-06-14 | — | — | EP | disclosed |
| US-20060030485-A1 | Herbicide/safener combinations | AVENTIS CROPSCIENCE GMBH | 2006-02-09 | — | — | US | disclosed |
| US-20050096228-A1 | Herbicidal compositions | BAYER CROPSCIENCE AG (DE) | 2005-05-05 | — | — | US | disclosed |
| US-6835695-B2 | For controlling harmful plants in crops | AVENTIS CROPSCIENCE GMBH (DE) | 2004-12-28 | — | — | US | disclosed |
| EP-1130965-B1 | COMBINATIONS OF HERBICIDES AND SAFENERS | BAYER CROPSCIENCE GMBH (DE) | 2003-10-29 | — | — | EP | disclosed |
| EP-1296558-A1 | HERBICIDAL AGENTS | Aventis CropScience GmbH (DE) | 2003-04-02 | — | — | EP | disclosed |
| US-20020137634-A1 | Herbicidal Compositions | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2002-09-26 | — | — | US | disclosed |
| WO-2001097614-A1 | HERBICIDAL AGENTS | BAYER CROPSCIENCE GMBH (DE) | 2001-12-27 | — | — | WO | disclosed |
| US-6297196-B1 | HETEROCYCLIC COMPOUNDS WITH KETONE GROUPS AND OXIMES, PHOSPHONATES OR PHOSPHATES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-10-02 | — | — | US | disclosed |
| EP-1109807-A1 | BENZOYL DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Aventis CropScience GmbH (DE) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014087-A1 | BENZOYL DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 2000-03-16 | — | — | WO | disclosed |
| US-5550630-A | Spectrophotometric method for structural analysis of organic compounds, polymers, nucleotides and peptides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1996-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322657-A1 | HERBICIDE/SAFENER COMBINTIONS | DDT, DERL1, SLC16A7 | TDP1 2235/4885L3MBTL1 291/4885LMNA 4284/4885 |
| US-20060030485-A1 | Herbicide/safener combinations | DDT, DERL1, SLC16A7 | TDP1 2399/4885L3MBTL1 246/4885LMNA 4311/4885 |
| US-20020137634-A1 | Herbicidal Compositions | CBR1, CBR3, CYCS | TDP1 1971/4885L3MBTL1 1199/4885LMNA 3269/4885 |
| US-20110053778-A1 | 2-(3-AMINOBENZOYL)-3-CYCLOPROPYL-3-OXOPROPANENITRILES AND THEIR USE AS HERBICIDES | CBR3, DDT, CNPY3 | TDP1 1418/4885L3MBTL1 1502/4885LMNA 2555/4885 |
| US-20100305200-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, ATP2A1 | TDP1 2959/4885L3MBTL1 3948/4885LMNA 1255/4885 |
| US-20050096228-A1 | Herbicidal compositions | CBR1, CBR3, CYP1A1 | TDP1 2533/4885L3MBTL1 1227/4885LMNA 3113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.