Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TKT | P29401 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ADA | P00813 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845265 | 0.84 | TSHR (0.40) | MEN1TSHRKMT2ATKT | |
| SCHEMBL9019796 | 0.83 | CYP3A4 (0.41) | CYP3A4CYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL9845279 | 0.80 | MEN1 (0.39) | MEN1TSHRKMT2ATKTSMN1; SMN2 | |
| SCHEMBL9845285 | 0.80 | PIK3CG (0.33) | CYP3A4CYP2D6CYP2C9CYP2C19TSHR | |
| SCHEMBL9019764 | 0.80 | PDE3A (0.38) | CYP3A4CYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL9845278 | 0.80 | SYK (0.31) | CYP3A4CYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL9019826 | 0.78 | ALDH1A1 (0.37) | CYP3A4CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL9019807 | 0.78 | PDE3A (0.32) | CYP3A4CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL9845246 | 0.76 | BCHE (0.36) | CYP3A4CYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL10405846 | 0.75 | MEN1 (0.42) | CYP3A4MEN1TSHRKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |