Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.36 |
| ▸ | CDK1 | P06493 | 7/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.34 |
| ▸ | CDK2 | P24941 | 7/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019771 | 0.91 | CDK1 (0.40) | TLR7CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL9019783 | 0.88 | ADORA2A (0.35) | TLR7CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL9019778 | 0.82 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL9019784 | 0.79 | ALDH1A1 (0.36) | — | |
| SCHEMBL9019744 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL9019822 | 0.75 | MEN1 (0.48) | — | |
| SCHEMBL9019742 | 0.72 | ACHE (0.33) | — | |
| SCHEMBL7981049 | 0.71 | TLR7 (0.39) | TLR7CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL9019773 | 0.71 | PDE3A (0.39) | — | |
| Rociclovir SCHEMBL29573658 | 0.69 | ALDH1A1 (0.49) | CDK1CCNB1CDK2HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-B1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |