Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019742 | 0.88 | ACHE (0.33) | ALDH1A1CYP1A2ACHEBCHE | |
| SCHEMBL9021299 | 0.87 | ACHE (0.42) | CYP1A2ACHEBCHE | |
| SCHEMBL9019743 | 0.86 | ACHE (0.33) | ACHEBCHE | |
| SCHEMBL9019807 | 0.80 | PDE3A (0.32) | ALDH1A1 | |
| SCHEMBL9019801 | 0.79 | TLR7 (0.36) | — | |
| SCHEMBL9021782 | 0.79 | ACHE (0.43) | CYP1A2ACHEBCHE | |
| SCHEMBL9019840 | 0.78 | HPGD (0.46) | ALDH1A1 | |
| SCHEMBL9021161 | 0.78 | BCHE (0.50) | ACHEBCHE | |
| SCHEMBL9019764 | 0.76 | PDE3A (0.38) | ALDH1A1 | |
| SCHEMBL7981316 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP1A2ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-B1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |