SCHEMBL9019859

SCHEMBL9019859

CC(C)(C)OC(=O)C[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.34
CYP2D6 P10635 1/20 0.34
CCNB2 O95067 1/20 0.34
CCNE2 O96020 1/20 0.34
CDK1 P06493 1/20 0.34
CDK4 P11802 1/20 0.34
CCNB1 P14635 1/20 0.34
CCND1 P24385 1/20 0.34
CCNE1 P24864 1/20 0.34
CDK2 P24941 1/20 0.34
CCNB3 Q8WWL7 1/20 0.34
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CA2 P00918 2/20 0.32
CTSK P43235 1/20 0.32
CA12 O43570 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14636958 0.83 DGAT1 (0.33) DGAT1CYP2D6CCNB2CCNE2CDK1
SCHEMBL4947910 0.81 GAA (0.32)
SCHEMBL21271556 0.76 DGAT1 (0.37) DGAT1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL29062743 0.76 MLYCD (0.38) DGAT1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL10010525 0.73 MEN1 (0.34) DGAT1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL5401041 0.73 DGAT1 (0.30) DGAT1
SCHEMBL644646 0.73 TSHR (0.45) DGAT1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL241533 0.73 DGAT1 (0.46) DGAT1CYP2D6HDAC3HDAC1HDAC2
SCHEMBL140084 0.70
SCHEMBL990791 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113265277-A Clean synthetic fuel for ignition type engine 国供能源(福建)有限公司 2021-08-17 CN claimed
CN-118995284-B Fuel additive for improving antiknock performance of gasoline and preparation method thereof 山东一鹏能源发展有限公司 2025-01-28 CN disclosed
CN-118995284-A Fuel additive for improving antiknock performance of gasoline and preparation method thereof 山东一鹏能源发展有限公司 2024-11-22 CN disclosed
CN-118995284-A Fuel additive for improving antiknock performance of gasoline and preparation method thereof 山东一鹏能源发展有限公司 2024-11-22 CN disclosed
CN-113265277-A Clean synthetic fuel for ignition type engine 国供能源(福建)有限公司 2021-08-17 CN disclosed
CN-108178732-B Preparation method of N-methyl p-methoxyaniline 中国科学院兰州化学物理研究所 2021-01-19 CN disclosed
CN-108178732-A A kind of preparation method of N- methyl P-nethoxyaniline 中国科学院兰州化学物理研究所 2018-06-19 CN disclosed
EP-2794564-B1 STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-02-24 EP disclosed
US-9131688-B2 Strigolactam derivatives as plant growth regulating compounds SYNGENTA PARTICIPATIONS AG (CH) 2015-09-15 US disclosed
US-20140336052-A1 STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2014-11-13 US disclosed
EP-0418175-B1 Isoxazoles herbicides RHONE POULENC AGRICULTURE (GB) 1996-07-17 EP disclosed
EP-0470856-B1 Isoxazole derivatives, process for their preparation and their herbicidal applications RHONE POULENC AGRICULTURE (GB) 1995-10-11 EP disclosed
EP-0470856-A1 Isoxazole derivatives, process for their preparation and their herbicidal applications RHONE-POULENC AGRICULTURE LTD. (GB) 1992-02-12 EP disclosed
US-5028629-A 2-(Substituted)-N-Hydroxy-N-Alkylcinnamamides ELI LILLY AND COMPANY (US) 1991-07-02 US disclosed
EP-0418175-A2 Isoxazoles herbicides RHONE POULENC AGRICULTURE LTD. (GB) 1991-03-20 EP disclosed
US-4874782-A PHOSPHOLIPASE INHIBITORS ELI LILLY AND COMPANY (US) 1989-10-17 US disclosed
EP-0107928-B1 VINYLTHIOACETAMIDO OXACEPHALOSPORIN DERIVATIVES, AND INTERMEDIATES THEREFOR, THEIR PREPARATION, FORMULATIONS CONTAINING THE SAME AND THEIR ANTIBACTERIAL USE SHIONOGI & CO., LTD. (JP) 1988-01-07 EP disclosed
EP-0209274-A2 Furanone derivatives ELI LILLY AND COMPANY (US) 1987-01-21 EP disclosed
US-4529721-A Human and veterinary bactericide SHIONOGI & CO., LTD. (JP) 1985-07-16 US disclosed
US-4448980-A BY CARBONYLATION WITH BIFLUORIDE CATALYSTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140336052-A1 STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS AREG, GHITM, GRK6 DGAT1 1419/4885CYP2D6 4347/4885CCNB2 968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.