Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.30 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.30 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28057460 | 0.84 | FBP1 (0.47) | FBP1MAOAMAOBNR1D1TAAR1 | |
| SCHEMBL9951459 | 0.79 | KIF11 (0.50) | FBP1MAOBTAAR1IDO1 | |
| SCHEMBL9322428 | 0.78 | LOXL2 (0.42) | CA1CA2CA9LOXL2IDO1 | |
| SCHEMBL2454131 | 0.76 | MAPT (0.44) | CA1CA2 | |
| SCHEMBL4973441 | 0.74 | CA1 (0.56) | CA1CA2CA5ACA9HSD11B1 | |
| SCHEMBL445417 | 0.74 | CA1 (0.56) | CA1CA2CA5ACA9HSD11B1 | |
| SCHEMBL18242747 | 0.73 | TAAR1 (0.35) | RORCMAOBTAAR1PTPN2PTPN1 | |
| SCHEMBL6818 | 0.73 | KCNJ1 (0.43) | FBP1MAOAMAOBLOXL2TAAR1 | |
| SCHEMBL25211439 | 0.72 | DAO (0.44) | — | |
| SCHEMBL18242285 | 0.69 | TAAR1 (0.42) | MAOBTAAR1PTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |